LEG ULCERS¹²

 

Vascular

• Arterial: arteriosclerosis, thromboangiitis obliterans, AV malformation cholesterol emboli.

• Venous: superficial varicosities, incompetent perforators, DVT, lymphatic abnormalities.

• Vasculitis Hematologic

• Sickle  cell   anemia,  thalasemia,  polycythemia  vera,  leukemia, cold agglutinin disease.

• Macroglobulinemia, protein C and protein S deficiency.

• Infectious

• Fungus:  Blastomycosis,  coccidioidomycosis,  histoplasmosis,  sporotrichosis.

• Bacterial: Furuncle, ecthyma, septic emboli. Protozoal: leishmaniasis.

• Metabolic

• Necrobiosis lipoidica diabeticorum.

• Localized bullous pemphigoid.

• Gout, calcinosis cutis, Gauchers disease.

• Tumors

• Basal cell carcinoma, squamous cell carcinoma, melanoma.

• Mycosis fungoides, Kaposi's sarcoma, metastatic neoplasms.

• Trauma

• Burns, cold injury, radiation dermatitis.

• Insect bites.

• Factitial, excessive pressure.

• Neuropathic

• Diabetic trophic ulcers.

• Tabes dorsalis, syringomyelia.

• Drugs

• Warfarin, IV colchicine extravasation, methotrexate, halogens, ergotism, hydroxyurea.

• Panniculitis

• Weber-Christian disease.

• Pancreatic fat necrosis, alpha-antitrypsinase deficiency.